Selank Anxiolytic Peptide Research Hub
Selank anxiolytic peptide research — tuftsin-derived heptapeptide, BDNF modulation, GABAergic mechanisms, immune regulation, cognitive enhancement, and anxiety model studies with citations.
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In-depth research profiles with mechanisms of action, key findings, and peer-reviewed citations.
Selank (TP-7)
Also known as: Selank, TP-7
Selank 11mg contains the same selank heptapeptide as the 10mg product — a synthetic derivative of tuftsin with anxiolytic, nootropic, and immunomodulatory properties. The mechanism involves GABA-A receptor modulation, enkephalin-degrading enzyme inhibition, and BDNF expression enhancement. See the Selank 10mg entry for comprehensive research details. The 11mg vial provides slightly more material ...
Quick Facts
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
MW: 751.89 g/mol
CAS: 129954-34-3
Store lyophilized powder at -20C. Reconstituted solution at 2-8C, use within 14-21 days.
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Read ArticleResearch Applications
Key research categories and applications studied in the scientific literature.
Cognitive Enhancement
Modulates neurotransmitters to enhance focus and reduce anxiety-related brain fog. Produces anxiolytic effects comparable to benzodiazepines without sedation or dependence.
Sleep Optimization
Acts as a potent anti-anxiety agent, reducing stress-related insomnia without causing sedation — addressing the cognitive root of sleep disturbance rather than forcing sedation.
Immune Support
Retains immunomodulatory activity from its parent molecule tuftsin — stimulating IL-6 production, enhancing phagocytic activity, and modulating Th1/Th2 immune balance.
Frequently Asked Questions
Common questions about selank research research, purity standards, and sourcing.
What is Selank?
Selank (TP-7) is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin (threonyl-lysyl-prolyl-arginine) with a C-terminal Pro-Gly-Pro extension that increases metabolic stability. It is studied for anxiolytic, nootropic, and immunomodulatory effects.
How does Selank reduce anxiety in research models?
Selank modulates GABAergic neurotransmission, increases BDNF expression in the hippocampus, and influences serotonin metabolism. In animal models, it produces anxiolytic effects comparable to benzodiazepines without sedation, motor impairment, or dependence.
Does Selank affect the immune system?
Yes. Selank's parent molecule tuftsin is a natural immunostimulant. Selank retains immunomodulatory activity — it stimulates IL-6 production, enhances phagocytic activity, and modulates the balance between Th1 and Th2 immune responses.
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